Generic Viagra (Sildenafil)

Indications

Treatment of erectile dysfunction, characterized by the inability to achieve or maintain an erection, sufficient for satisfactory sexual intercourse. Sildenafil is effective only in the case of sexual stimulation.

Contraindications

• The use in patients receiving continuously or intermittently nitric oxide donors, organic nitrates or nitrites in any other form, since sildenafil enhances the hypotensive effect of nitrates;
• The simultaneous use of the drug with other agents for the treatment of erectile dysfunction (the safety and effectiveness of combination therapy has not been studied);
• Children’s and teenage age up to 18 years;
• Women;
• Hypersensitivity to sildenafil or to any component of the drug.
• Take the drug with caution if you have an anatomical deformation of the penis (including during angulation, cavernous fibrosis, or Peyronie’s disease);
• In diseases predisposing to the development of priapism (such as sickle cell anemia, multiple myeloma, leukemia, thrombocytopenia);
• Diseases accompanied by bleeding;
• Exacerbation of peptic ulcer of the stomach and duodenum;
• Hereditary retinitis pigmentosa;
• Heart failure, unstable angina, suffered in the last 6 months, myocardial infarction, stroke, severe, life-threatening arrhythmias, arterial hypertension (blood pressure over 170/100 mm Hg) or hypotension (blood pressure below 90/50 mm Hg).

Side effects

The most common side effects were a headache and hot flashes.

Side effects are usually mild or moderate and transient.

In studies using a fixed-dose, it was found that the frequency of some adverse events increases when the dose is enhanced.

• The immune system: infrequently – hypersensitivity reactions (including skin rash), allergic reactions.
• The organ of vision: often – blurred vision, impaired vision, cyanopsia; infrequently – pain in the eyes, photophobia, photopsy, chromatopsia, redness of the eyes/injection of sclera, changes in brightness of light perception, mydriasis, conjunctivitis, hemorrhage in the tissue of the eye, cataracts, malfunctioning of the lacrimal apparatus; rarely – swelling of the eyelids and adjacent tissues, a feeling of dryness in the eyes, the presence of rainbow circles in the field of view around the light source, increased eye fatigue, seeing objects in yellow (xanthopsia), seeing objects in red (erythroplasia), conjunctival hyperemia, irritation of the mucous membrane eye, discomfort in the eyes; the frequency is unknown – non-arteritic anterior ischemic optic neuropathy, retinal vein occlusion, visual field defect, diplopia, temporary loss of vision or decreased visual acuity, increased intraocular pressure, retinal edema, retinal vascular disease, vitreous detachment/vitreous traction.
• The hearing organ: infrequently – a sudden decrease or loss of hearing, tinnitus, earache.
• The cardiovascular system: often – “hot flashes”; infrequently – tachycardia, palpitations, decreased blood pressure, increased heart rate, unstable angina, AV block, myocardial ischemia, cerebral thrombosis, cardiac arrest, heart failure, ECG abnormalities, cardiomyopathy; rarely – atrial fibrillation.
• The hemopoietic system: infrequently – anemia, leukopenia.
• Metabolism and nutrition: infrequently – thirst, swelling, gout, uncompensated diabetes, hyperglycemia, peripheral edema, hyperuricemia, hypoglycemia, hypernatremia.
• The respiratory system: often – nasal congestion; infrequently – nosebleeds, rhinitis, asthma, dyspnea, laryngitis, pharyngitis, sinusitis, bronchitis, increased sputum discharge, increased cough; rarely – a feeling of tightness in the throat, dryness of the mucous membrane of the nasal cavity, swelling of the nasal mucosa.
• The digestive system: often – nausea, dyspepsia; infrequently – gastroesophageal reflux disease, vomiting, abdominal pain, dry mouth, glossitis, gingivitis, colitis, dysphagia, gastritis, gastroenteritis, esophagitis, stomatitis, abnormal liver function tests, rectal bleeding; rarely – hypoesthesia of the oral mucosa.
• The musculoskeletal system: often – back pain; infrequently – myalgia, pain in the limbs, arthritis, arthrosis, tendon rupture, tenosynovitis, bone pain, myasthenia gravis, synovitis.
• The genitourinary system: infrequently – cystitis, nocturia, breast enlargement, urinary incontinence, hematuria, impaired ejaculation, genital edema, anorgasmia, penile tissue damage; rarely – prolonged erection known as priapism.
• The central and peripheral nervous system: very often – headache; often – dizziness; infrequently – drowsiness, migraine, ataxia, hypertonicity, neuralgia, neuropathy, paresthesia, tremor, vertigo, symptoms of depression, insomnia, unusual dreams, increased reflexes, hypesthesia; rarely – convulsions, repeated convulsions, fainting.
• The skin and subcutaneous tissues: infrequently – a skin rash, urticaria, herpes simplex, itching, increased sweating, skin ulceration, contact dermatitis, exfoliative dermatitis; frequency unknown – Stevens-Johnson syndrome, toxic epidermal necrolysis.
• Other: infrequently – a feeling of heat, swelling of the face, photosensitivity reactions, shock, asthenia, increased fatigue, pain of various localization, chills, accidental falls, pain in the chest area, accidental injuries; rarely irritability.

Overdose

With a single dose of the drug up to 800 mg, adverse events were comparable to those with sildenafil at lower doses but were more common.

Treatment: symptomatic therapy. Hemodialysis does not accelerate clearance of sildenafil, as the latter actively binds to plasma proteins and is not excreted in the urine.

Disclaimer: Generic Viagra is a medical product and can only be taken after examination and appointment by a healthcare practitioner. The site administration is not responsible for side effects and any harm to health associated with self-medication with drugs based on Sildenafil. Please follow contraindications and dosage. Increased dosage and frequent use can harm health.